Focuses on a group of toddlers, most prominently Tommy, Chuckie, Phil, Lil, and Angelica, and their day-to-day lives, usually involving common life experiences that become adventures in the babies' imaginations. Adults in the series are almost always unaware of what the children are up to; however, this only provides more room for the babies to explore and discover their surroundings.

Cast

E. G. Daily

Tommy Pickles (voice)

Kath Soucie

Phil DeVille / Lil DeVille (voice)

Cheryl Chase

Angelica Pickles (voice)

Melanie Chartoff

Didi Pickles (voice)

Jack Riley

Stu Pickles (voice)

Michael Bell

Drew Pickles / Chas Finster (voice)

Tress MacNeille

Charlotte Pickles (voice)

Cree Summer

Susie Carmichael (voice)

Christine Cavanaugh

Chuckie Finster (voice)

Joe Alaskey

Lou Pickles (voice)

David Doyle

Lou Pickles (voice)

Tara Strong

Timmy McNulty / Teddy McNulty (voice)

Dionne Quan

Kimi Finster (voice)

Julia Kato

Kira Finster (voice)

Nancy Cartwright

Boy / Brat / Nick (voice)

Phil Proctor

Intern / Dr. Lecter (voice)

Tony Jay

General (voice)

Dana Hill

Josh (voice)

Scott Menville

Batboy / Bucky Majors (voice)

Amanda Bynes

Taffy

Seasons

322 episodes

Season 11991 · 25 episodes

Season 21992 · 51 episodes

Season 31993 · 50 episodes

Season 41997 · 27 episodes

Season 51998 · 25 episodes

Season 61999 · 32 episodes

Season 71999 · 18 episodes

Season 82000 · 63 episodes

Season 92002 · 31 episodes