Some memories are best forgotten.

Leonard Shelby is tracking down the man who raped and murdered his wife. The difficulty of locating his wife's killer, however, is compounded by the fact that he suffers from a rare, untreatable form of short-term memory loss. Although he can recall details of life before his accident, Leonard cannot remember what happened fifteen minutes ago, where he's going, or why.

Cast

Guy Pearce

Leonard

Carrie-Anne Moss

Natalie

Joe Pantoliano

Teddy

Mark Boone Junior

Burt

Russ Fega

Waiter

Jorja Fox

Leonard's Wife

Stephen Tobolowsky

Sammy

Harriet Sansom Harris

Mrs. Jankis

Thomas Lennon

Doctor

Callum Keith Rennie

Dodd

Kimberly Campbell

Blonde

Marianne Muellerleile

Tattooist

Larry Holden

Jimmy